Royal Air Force Typhoon FGR4s have operated alongside French aircraft in a combined operation against an subterranean weapons facility in Syrian territory used by the Islamic State group (IS), according to the British defence ministry.
The site, located using reconnaissance, was assessed as containing munitions and bombs, the announcement noted, and was situated in hills just to the north of the ancient city of Palmyra in Syria's central region.
"The RAF jets utilized Paveway IV guided bombs to target a series of entry passages leading to the depot... preliminary assessments suggest the target was engaged successfully," officials stated.
There was no sign of any civilian impact in the operation late on Saturday and all the aircraft made a safe return, the MoD added.
The Typhoon FGR4s were supported by a Voyager aerial refuelling aircraft.
Daesh - alternatively referred to as Daesh - established militant control over parts of Syria and Iraq until 2019.
"This operation shows British leadership, and commitment to work closely with our partners, to eradicate any revival of Daesh and their harmful and extremist ideologies in the Middle East," Britain's Defence Chief John Healey stated.
UK warplanes have performed surveillance missions over Syria to "deter any attempted resurgence" of Islamic State after its defeat at the battle of Baghuz in the year 2019, the authorities noted.
"I want to thank the personnel of the UK armed forces involved in this operation for their skill and their valour," the Defence Secretary added. "They were part of thousands of British troops stationed over the festive period. This mission, to take out terrorist threats who threaten our security, highlights how our armed forces are ready to step up, all year round, protecting the UK at home and powerful internationally."
In December, the United States armed forces carried out what it termed a "major assault" on Daesh sites in the country, following an assault killed two American soldiers and a civilian linguist in Palmyra.
The United Nations reports Islamic State still has roughly 5-7 thousand fighters in Syria and Iraq.